Dr. Ayeni is a Professor and Academic Division Head of Orthopaedic Surgery at McMaster University, Canada. He is also an Adjunct Professor in the Department of Health Research Methodology, Evidence and Impact and Medical Director for the Hamilton Tiger Cats (Canadian Football League) and Forge FC (Canadian Premier League). Dr. Ayeni has been named a Tier 2 Canada Research Chair in Joint Preservation Surgery (2022-2027) by the Canadian Institutes of Health Research and a University Scholar (2022-2026) at McMaster University. He is the President of the Canadian Orthopaedic Association 2024-2025.

He has published over 400 academic publications in sports medicine and related research, as well as edited several textbooks. Dr. Ayeni is the Co-Chair for the International Society of Arthroscopy, Knee Surgery and Orthopaedic Sports Medicine (ISAKOS) Scientific Committee (2023) and Research Committee Chair for the International Society for Hip Arthroscopy (2021). Recently, he completed roles as Deputy Editor in Chief for the journal of Knee Surgery Sports Traumatology and Arthroscopy (KSSTA) and Scientific Editor for the Canadian Orthopaedic Association Bulletin and is now the Editor-in Chief for the Journal of ISAKOS. His clinical practice and research focus on minimally invasive orthopaedic interventions that treat joint injuries with the aim to prevent degenerative joint disease.